Title : Understanding the effects of atrazine on steroidogenesis in rat granulosa and H295R adrenal cortical carcinoma cells.

Pub. Date : 2011 Feb

PMID : 21126571






4 Functional Relationships(s)
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1 Atrazine (10 muM), but not its metabolite, 2-chloro-4,6-diamino-1,2,5-triazine (DACT), significantly increased estradiol production and aromatase activity in granulosa cell cultures only when measured for 1-h following 24h of exposure. Atrazine latexin Homo sapiens
2 In H295R cells, atrazine (10 muM) increased estradiol and estrone production. Atrazine latexin Homo sapiens
3 Importantly, atrazine (10 muM) increased progesterone production from both cell types suggesting a broader effect of atrazine on steroidogenesis. Atrazine latexin Homo sapiens
4 Importantly, atrazine (10 muM) increased progesterone production from both cell types suggesting a broader effect of atrazine on steroidogenesis. Atrazine latexin Homo sapiens