Title : Sildenafil is more selective pulmonary vasodilator than prostaglandin E1 in patients with pulmonary hypertension due to heart failure.

Pub. Date : 2011

PMID : 21114369






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Sildenafil has been recently recognized as potent PVR-lowering drug in HF. Sildenafil Citrate PVR cell adhesion molecule Homo sapiens
2 Both drugs similarly reduced systemic vascular resistance (SVR), but sildenafil had higher effect on PVR (-28 % vs. -49 %, p = 0.05) and transpulmonary pressure gradient than PGE(1). Sildenafil Citrate PVR cell adhesion molecule Homo sapiens
3 Sildenafil led more often to transplant-acceptable PVR while causing smaller drop of mean systemic pressure than PGE(1). Sildenafil Citrate PVR cell adhesion molecule Homo sapiens