Title : Akt contributes to activation of the TRIF-dependent signaling pathways of TLRs by interacting with TANK-binding kinase 1.

Pub. Date : 2011 Jan 1

PMID : 21106850






1 Functional Relationships(s)
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1 Blockade of Akt by a dominant-negative mutant or by short interfering RNA decreased IRF3 activation and IFN-beta expression induced by polyinosinic:polycytidylic acid [poly(I:C)], LPS, TRIF, and TBK1. Poly C interferon beta 1, fibroblast Mus musculus