Pub. Date : 2011 Apr
PMID : 21106690
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In fungiform and vallate TRCs that exhibit functional ENaC currents (e.g., amiloride-sensitive Na(+) influx), insulin (5-20 nM) caused a significant increase in Na(+) influx at -80 mV (EC(50) = 7.53 nM). | Amiloride | sodium channel, nonvoltage-gated 1 alpha | Mus musculus |
2 | Interestingly, these differences between groups were abolished when amiloride (100 muM) was added into NaCl solutions, suggesting that insulin was regulating ENaC. | Amiloride | sodium channel, nonvoltage-gated 1 alpha | Mus musculus |