Title : Proline residues link the active site to transmembrane domain movements in human nucleoside triphosphate diphosphohydrolase 3 (NTPDase3).

Pub. Date : 2010 Sep

PMID : 21103216






2 Functional Relationships(s)
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Protein Name
Organism
1 Proline to alanine substitutions at P53, P481, P484, and P485 in the V42C background, as well as P53, P481, and P484 in the G489C background, exhibited decreased nucleotidase activities. Alanine tumor protein p53 Homo sapiens
2 More importantly, alanine substitutions at P53 and P481 in the V42C background and P481 in the G489C background no longer exhibited the ATP-induced decrease in transmembrane cross-linking efficiency. Alanine tumor protein p53 Homo sapiens