Pub. Date : 2010 Sep-Oct
PMID : 21098866
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metformin has adenosine-monophosphate activated protein kinase (AMPK)-independent effects on LPS-stimulated rat primary microglial cultures. | Metformin | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |
| 2 | Adenosine-monophosphate-activated protein kinase (AMPK) activation is the most well-known mechanism of metformin action; however, some of the biological responses to metformin are not limited to AMPK activation but are mediated by AMPK-independent mechanisms. | Metformin | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |
| 3 | Adenosine-monophosphate-activated protein kinase (AMPK) activation is the most well-known mechanism of metformin action; however, some of the biological responses to metformin are not limited to AMPK activation but are mediated by AMPK-independent mechanisms. | Metformin | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |
| 4 | Adenosine-monophosphate-activated protein kinase (AMPK) activation is the most well-known mechanism of metformin action; however, some of the biological responses to metformin are not limited to AMPK activation but are mediated by AMPK-independent mechanisms. | Metformin | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |
| 5 | Adenosine-monophosphate-activated protein kinase (AMPK) activation is the most well-known mechanism of metformin action; however, some of the biological responses to metformin are not limited to AMPK activation but are mediated by AMPK-independent mechanisms. | Metformin | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |
| 6 | Adenosine-monophosphate-activated protein kinase (AMPK) activation is the most well-known mechanism of metformin action; however, some of the biological responses to metformin are not limited to AMPK activation but are mediated by AMPK-independent mechanisms. | Metformin | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |
| 7 | Adenosine-monophosphate-activated protein kinase (AMPK) activation is the most well-known mechanism of metformin action; however, some of the biological responses to metformin are not limited to AMPK activation but are mediated by AMPK-independent mechanisms. | Metformin | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |
| 8 | The presented evidence supports the conclusion that metformin-activated AMPK participates in regulating the release of TNF-alpha. | Metformin | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |