Title : Conformational remodeling of femtomolar inhibitor-acetylcholinesterase complexes in the crystalline state.

Pub. Date : 2010 Dec 29

PMID : 21090615






1 Functional Relationships(s)
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1 The click-chemistry inhibitor TZ2PA6 links the active center ligand, tacrine, to the peripheral site ligand, propidium, through a biorthogonal reaction of an acetylene and an azide that forms either a syn1 or an anti1 triazole. Azides synapsin I Mus musculus