Title : Effects of prostacyclin on bronchoconstriction and neutropenia induced by inhaled platelet-activating factor in man.

Pub. Date : 1990 Apr

PMID : 2109002






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1 Effects of prostacyclin on bronchoconstriction and neutropenia induced by inhaled platelet-activating factor in man. Epoprostenol PCNA clamp associated factor Homo sapiens
2 We studied the effects of prostacyclin (PGI2) on the airway responses to platelet-activating factor (PAF) in a randomized and crossover study in eight normal subjects. Epoprostenol PCNA clamp associated factor Homo sapiens
3 We studied the effects of prostacyclin (PGI2) on the airway responses to platelet-activating factor (PAF) in a randomized and crossover study in eight normal subjects. Epoprostenol PCNA clamp associated factor Homo sapiens
4 We studied the effects of prostacyclin (PGI2) on the airway responses to platelet-activating factor (PAF) in a randomized and crossover study in eight normal subjects. Epoprostenol PCNA clamp associated factor Homo sapiens
5 We studied the effects of prostacyclin (PGI2) on the airway responses to platelet-activating factor (PAF) in a randomized and crossover study in eight normal subjects. Epoprostenol PCNA clamp associated factor Homo sapiens
6 Ex vivo platelet aggregation to PAF (10(-9) to 10(-7) mol/L) was significantly inhibited by PGI2. Epoprostenol PCNA clamp associated factor Homo sapiens
7 Thus, PGI2 does not influence PAF-induced bronchoconstriction in man despite causing marked inhibition of ex vivo PAF-induced platelet aggregation and preventing the fall of neutrophils. Epoprostenol PCNA clamp associated factor Homo sapiens