Title : Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer.

Pub. Date : 2012 Apr

PMID : 21080209






1 Functional Relationships(s)
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1 Experimental results revealed that LMWH (Enoxaparin, 3500-5500 Da) inhibited the CXCL12-stimulated proliferation, adhesion and colony formation of human colon cancer HCT-116 cells that highly expressed CXCR4. Enoxaparin C-X-C motif chemokine receptor 4 Homo sapiens