Title : Y1767C, a novel SCN5A mutation, induces a persistent Na+ current and potentiates ranolazine inhibition of Nav1.5 channels.

Pub. Date : 2011 Jan

PMID : 21076026






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 One LQT3 patient carried a mutation in the SCN5A gene in which the cysteine was substituted for a highly conserved tyrosine (Y1767C) located near the cytoplasmic entrance of the Na(v)1.5 channel pore. Tyrosine immunoglobulin lambda variable 2-18 Homo sapiens