Title : Modulation of a GEF switch: autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEF.

Pub. Date : 2011 Jan

PMID : 21064165






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 All RGS-RhoGEFs possess tandemly linked Dbl-homology (DH) and plekstrin-homology (PH) domains, which bind and catalyze the exchange of GDP for GTP on RhoA. Guanosine Triphosphate paired like homeodomain 2 Homo sapiens