Title : Technetium-99m-labeled Arg-Gly-Asp-conjugated alpha-melanocyte stimulating hormone hybrid peptides for human melanoma imaging.

Pub. Date : 2010 Nov

PMID : 21055617






4 Functional Relationships(s)
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1 Technetium-99m-labeled Arg-Gly-Asp-conjugated alpha-melanocyte stimulating hormone hybrid peptides for human melanoma imaging. Arginine proopiomelanocortin Homo sapiens
2 INTRODUCTION: The purpose of this study was to examine whether (99m)Tc-labeled Arg-Gly-Asp (RGD)-conjugated alpha-melanocyte stimulating hormone (alpha-MSH) hybrid peptide targeting both melanocortin-1 (MC1) and alpha(v)beta(3) integrin receptors was superior in melanoma targeting to (99m)Tc-labeled alpha-MSH or RGD peptide targeting only the MC1 or alpha(v)beta(3) integrin receptor. Arginine proopiomelanocortin Homo sapiens
3 INTRODUCTION: The purpose of this study was to examine whether (99m)Tc-labeled Arg-Gly-Asp (RGD)-conjugated alpha-melanocyte stimulating hormone (alpha-MSH) hybrid peptide targeting both melanocortin-1 (MC1) and alpha(v)beta(3) integrin receptors was superior in melanoma targeting to (99m)Tc-labeled alpha-MSH or RGD peptide targeting only the MC1 or alpha(v)beta(3) integrin receptor. Arginine proopiomelanocortin Homo sapiens
4 INTRODUCTION: The purpose of this study was to examine whether (99m)Tc-labeled Arg-Gly-Asp (RGD)-conjugated alpha-melanocyte stimulating hormone (alpha-MSH) hybrid peptide targeting both melanocortin-1 (MC1) and alpha(v)beta(3) integrin receptors was superior in melanoma targeting to (99m)Tc-labeled alpha-MSH or RGD peptide targeting only the MC1 or alpha(v)beta(3) integrin receptor. Arginine proopiomelanocortin Homo sapiens