Title : Partial agonists of the α3β4* neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats.

Pub. Date : 2011 Feb

PMID : 21048701






1 Functional Relationships(s)
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1 Recent human genetic association studies have implicated the gene cluster CHRNA3-CHRNA5-CHRNB4 encoding the alpha3, alpha5, and beta4 subunits of the nAChR in susceptibility to develop nicotine and alcohol dependence; however, their role in ethanol-mediated behaviors is unknown due to the lack of suitable and selective research tools. Nicotine cholinergic receptor nicotinic beta 4 subunit Homo sapiens