Title : Vandetanib mediates anti-leukemia activity by multiple mechanisms and interacts synergistically with DNA damaging agents.

Pub. Date : 2012 Apr

PMID : 21046425






1 Functional Relationships(s)
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1 Vandetanib is an orally active small molecule tyrosine kinase inhibitor (TKI) with activity against several pathways implicated in malignancy including the vascular endothelial growth factor receptor pathway, the epidermal growth factor receptor pathway, the platelet derived growth factor receptor beta pathway, and REarranged during Transfection pathway. vandetanib platelet derived growth factor receptor beta Homo sapiens