Pub. Date : 2011 Jan 7
PMID : 21044951
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we demonstrate that the heart-type fatty acid-binding protein, FABP3, is essential for cold tolerance and efficient fatty acid oxidation in mouse brown adipose tissue, despite the abundant expression of adipose-type fatty acid-binding protein, FABP4 (also known as aP2). | Fatty Acids | fatty acid binding protein 3, muscle and heart | Mus musculus |
| 2 | Here, we demonstrate that the heart-type fatty acid-binding protein, FABP3, is essential for cold tolerance and efficient fatty acid oxidation in mouse brown adipose tissue, despite the abundant expression of adipose-type fatty acid-binding protein, FABP4 (also known as aP2). | Fatty Acids | fatty acid binding protein 3, muscle and heart | Mus musculus |
| 3 | Here, we demonstrate that the heart-type fatty acid-binding protein, FABP3, is essential for cold tolerance and efficient fatty acid oxidation in mouse brown adipose tissue, despite the abundant expression of adipose-type fatty acid-binding protein, FABP4 (also known as aP2). | Fatty Acids | fatty acid binding protein 3, muscle and heart | Mus musculus |
| 4 | However, using FABP3 gain- and loss-of-function approaches in brown adipocytes, we detected a correlation between FABP3 levels and the utilization of exogenous fatty acids. | Fatty Acids | fatty acid binding protein 3, muscle and heart | Mus musculus |
| 5 | However, using FABP3 gain- and loss-of-function approaches in brown adipocytes, we detected a correlation between FABP3 levels and the utilization of exogenous fatty acids. | Fatty Acids | fatty acid binding protein 3, muscle and heart | Mus musculus |
| 6 | These results suggest that FABP3 levels are a determinant of fatty acid oxidation efficiency by brown adipose tissue and that FABP3 represents a potential target for modulation of energy dissipation. | Fatty Acids | fatty acid binding protein 3, muscle and heart | Mus musculus |