Title : Effects of MEK and DNMT inhibitors on arsenic-treated human uroepithelial cells in relation to Cyclin-D1 and p16.

Pub. Date : 2011 Jan 15

PMID : 21040761






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In addition, the Cyclin-D1 increased expression but decreased p16 expression in arsenite-treated SV-HUC-1 cells. arsenite cyclin D1 Homo sapiens
2 However, when cells were pretreated with inhibitors (5-aza-CdR or U0126), the effects of arsenite on Cyclin-D1 and p16 expression were suppressed. arsenite cyclin D1 Homo sapiens