Title : Doxycycline attenuates acrolein-induced mucin production, in part by inhibiting MMP-9.

Pub. Date : 2011 Jan 10

PMID : 21036164






3 Functional Relationships(s)
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1 Doxycycline attenuates acrolein-induced mucin production, in part by inhibiting MMP-9. Acrolein solute carrier family 13 member 2 Rattus norvegicus
2 The aim of this study was to investigate whether doxycycline, a tetracycline antibiotic that inhibits MMPs, attenuates mucus production and synthesis of mucin MUC5AC in acrolein-exposed rats. Acrolein solute carrier family 13 member 2 Rattus norvegicus
3 These results indicate that doxycycline attenuated acrolein-induced mucin synthesis, in part by inhibiting expression of MMP-9. Acrolein solute carrier family 13 member 2 Rattus norvegicus