Title : A gene signature-based approach identifies thioridazine as an inhibitor of phosphatidylinositol-3'-kinase (PI3K)/AKT pathway in ovarian cancer cells.

Pub. Date : 2011 Jan

PMID : 21035837






1 Functional Relationships(s)
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1 Exposure to thioridazine induced G(0)/G(1) arrest and down-regulated the cell cycle regulator, Cyclin D1 and CDK4, and up-regulated p21, p16, and p-CDC25A. Thioridazine cyclin D1 Homo sapiens