Title : [The role of opioid antagonists in the treatment of obesity. Results of a clinical trial with naltrexone].

Pub. Date : 1990 Apr-Jun

PMID : 2098653






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1 On the basis of literature data relative to the alteration of beta-endorphin tone in obese subjects, we conducted a clinical trial employing Naltrexone (a receptorial antagonist of endogen opioids) in order to evaluate its efficacy in increasing the compliance of these subjects on dietary treatment. Naltrexone proopiomelanocortin Homo sapiens