Pub. Date : 2011 Feb
PMID : 20973777
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Salinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 protein. | salinomycin | H3 histone pseudogene 16 | Homo sapiens |
| 2 | The level of anti-apoptotic p21 protein was increased by DOX or ETO but decreased by Sal, which increased proteasome activity. | salinomycin | H3 histone pseudogene 16 | Homo sapiens |
| 3 | Overall, we demonstrated that the ability of Sal to sensitize cancer cells to the effects of DOX or ETO is associated with an increase in DNA damage and a decrease in anti-apoptotic protein p21 levels. | salinomycin | H3 histone pseudogene 16 | Homo sapiens |