Title : Activation of the NLRP3 inflammasome by intracellular poly I:C.

Pub. Date : 2010 Nov 19

PMID : 20971108






1 Functional Relationships(s)
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1 We show here that transfection of the dsRNA analogue poly I:C activates the NLRP3 inflammasome via a pathway requiring endosomal acidification. Poly I-C NLR family pyrin domain containing 3 Homo sapiens