Title : Berberine attenuates cAMP-induced lipolysis via reducing the inhibition of phosphodiesterase in 3T3-L1 adipocytes.

Pub. Date : 2011 Apr

PMID : 20969954






2 Functional Relationships(s)
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Protein Name
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1 Berberine stimulated HSL Ser-565 as well as adenosine monophosphate-activated protein kinase (AMPK) phosphorylation. Berberine protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus
2 These results suggest that berberine exerts an antilipolytic effect mainly by reducing the inhibition of PDE, leading to a decrease in cAMP and HSL phosphorylation independent of AMPK pathway. Berberine protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus