Title : In utero and lactational exposure to a complex mixture of polychlorinated biphenyls: toxicity in pups dependent on the Cyp1a2 and Ahr genotypes.

Pub. Date : 2011 Jan

PMID : 20961953






1 Functional Relationships(s)
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1 Coplanar PCB concentrations were generally higher in Ahr(d)-containing pup tissues; these findings are consistent with earlier studies demonstrating the crucial importance of AHR-mediated inducible CYP1 in the gastrointestinal tract as a means of detoxication of oral planar polycyclic aromatic hydrocarbons. Polycyclic Aromatic Hydrocarbons pyruvate carboxylase Homo sapiens