Title : Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors.

Pub. Date : 2011 Jan

PMID : 20959532






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 In THP-1 cells, palmitate increased cellular TLR2 and TLR4 expression, generated reactive oxygen species (ROS), and increased NF-kappaB activity, IL-1beta, and MCP-1 release in a dose- and time-dependent manner. Palmitates C-C motif chemokine ligand 2 Homo sapiens