Title : Phosphorylated TP63 induces transcription of RPN13, leading to NOS2 protein degradation.

Pub. Date : 2010 Dec 31

PMID : 20959455






1 Functional Relationships(s)
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1 Head and neck squamous cell carcinoma cells exposed to cisplatin display ATM-dependent phosphorylation of the most predominant TP63 isoform (DeltaNp63alpha), leading to its activation as a transcription factor. Cisplatin tumor protein p63 Homo sapiens