Pub. Date : 2011 Jan 2
PMID : 20952260
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The DNA pol kappa was maximally activated to similar levels by a twenty-fold lower concentration of Mn(2+) compared to Mg(2+). | Manganese(2+) | DNA polymerase lambda | Homo sapiens |
| 2 | Strikingly, Mn(2+) activation of DNA pol kappa resulted in a dramatically lower efficiency of correct nucleotide incorporation opposite both N(2)-ethyl-Gua and Gua compared to that detected upon Mg(2+) activation. | Manganese(2+) | DNA polymerase lambda | Homo sapiens |
| 3 | A rapid kinetic analysis showed diminished burst amplitudes in the presence of Mn(2+) compared to Mg(2+) indicating that DNA pol kappa preferentially utilizes Mg(2+) activation. | Manganese(2+) | DNA polymerase lambda | Homo sapiens |