Title : The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells.

Pub. Date : 2010 Oct 15

PMID : 20950443






1 Functional Relationships(s)
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1 RESULTS: Sorafenib inhibited the proliferation of ALL cells by cell cycle arrest accompanied by down-regulation of CyclinD3 and CDK4. Sorafenib cyclin dependent kinase 4 Homo sapiens