Title : An essential role for Ran GTPase in epithelial ovarian cancer cell survival.

Pub. Date : 2010 Oct 13

PMID : 20942967






1 Functional Relationships(s)
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1 RESULTS: Using a lentivirus-based tetracycline-inducible shRNA approach, we show that downregulation of Ran expression in aggressive ovarian cancer cell lines affects cellular proliferation by inducing a caspase-3 associated apoptosis. Tetracycline caspase 3 Homo sapiens