Title : Dual role of NO donors in the reversal of tumor cell resistance and EMT: Downregulation of the NF-κB/Snail/YY1/RKIP circuitry.

Pub. Date : 2011 Jan 1

PMID : 20933602






1 Functional Relationships(s)
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1 Hence, we have found that treatment of metastatic cancer cell lines with DETANONOate inhibited the EMT phenotype, through both the inhibition of the metastasis-inducers, NF-kappaB and Snail and the induction of the metastasis-suppressor, RKIP. 2,2'-(hydroxynitrosohydrazono)bis-ethanamine phosphatidylethanolamine binding protein 1 Homo sapiens