Pub. Date : 2011 Jan 15
PMID : 20933509
2 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | The synergistic cytotoxicity of clofarabine, fludarabine and busulfan in AML cells involves ATM pathway activation and chromatin remodeling. | Busulfan | ATM serine/threonine kinase | Homo sapiens | ||
| 2 | The [Clo+Flu+Bu] combination activates an intense DNA damage response through the ATM pathway, leading to cell cycle checkpoint activation and apoptosis. | Busulfan | ATM serine/threonine kinase | Homo sapiens | ||