Title : Alcohol inhibits smooth muscle cell proliferation via regulation of the Notch signaling pathway.

Pub. Date : 2010 Dec

PMID : 20930168






3 Functional Relationships(s)
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1 EtOH treatment also decreased C-promoter binding factor-1 (CBF-1)/recombination signal-binding protein (RBP)-jk promoter activity and Notch target gene (hairy related transcription factor [HRT-1] or HRT-2) expression. Ethanol hes related family bHLH transcription factor with YRPW motif 1 Homo sapiens
2 Overexpression of constitutively active Notch 1 intracellular domain or human hairy related transcription factor-1 (hHRT-1) prevented the EtOH-induced inhibition of SMC proliferation. Ethanol hes related family bHLH transcription factor with YRPW motif 1 Homo sapiens
3 Overexpression of constitutively active Notch 1 intracellular domain or human hairy related transcription factor-1 (hHRT-1) prevented the EtOH-induced inhibition of SMC proliferation. Ethanol hes related family bHLH transcription factor with YRPW motif 1 Homo sapiens