Title : Hepatic and HSC-specific sorafenib effects in rats with established secondary biliary cirrhosis.

Pub. Date : 2011 Feb

PMID : 20921950






2 Functional Relationships(s)
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1 In BDL rats and isolated HSCs, the treatment with sorafenib reduced hepatic alphaSMA and procollagen-1alpha mRNA expression. Sorafenib actin gamma 2, smooth muscle Rattus norvegicus
2 As shown by immunohistochemical staining, perisinusoidal alphaSMA expression was reduced by sorafenib in BDL rats. Sorafenib actin gamma 2, smooth muscle Rattus norvegicus