Title : Increased stability of Bcl-2 in HSP70-mediated protection against apoptosis induced by oxidative stress.

Pub. Date : 2011 Mar

PMID : 20890773






1 Functional Relationships(s)
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1 An antisense phosphorothioate oligonucleotide against Bcl-2 caused selective inhibition of Bcl-2 protein expression induced by HSP70 and significantly attenuated HSP70-mediated cell protection against H(2)O(2)-induced release of Smac and apoptosis. Phosphorothioate Oligonucleotides diablo, IAP-binding mitochondrial protein Mus musculus