Title : Suppressing LPS-induced early signal transduction in macrophages by a polyphenol degradation product: a critical role of MKP-1.

Pub. Date : 2011 Jan

PMID : 20884647






1 Functional Relationships(s)
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1 By reversing LPS-induced early suppression of MKP-1, ferulaldehyde diminished MAPK activation, thereby inhibiting NF-kappaB activation, mitochondrial depolarization, and ROS production. ferulaldehyde mitogen-activated protein kinase 1 Mus musculus