Pub. Date : 2011 Jan
PMID : 20881032
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aryl hydrocarbon receptor pathway and the response to 3-methylcholanthrene are altered in the liver of adrenalectomized rats. | Methylcholanthrene | aryl hydrocarbon receptor | Rattus norvegicus |
| 2 | The aryl hydrocarbon receptor (AHR) is activated by 3-methylcholanthrene (MC), a polycyclic aromatic hydrocarbon, and environmental contaminants, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin. | Methylcholanthrene | aryl hydrocarbon receptor | Rattus norvegicus |
| 3 | The aryl hydrocarbon receptor (AHR) is activated by 3-methylcholanthrene (MC), a polycyclic aromatic hydrocarbon, and environmental contaminants, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin. | Methylcholanthrene | aryl hydrocarbon receptor | Rattus norvegicus |
| 4 | The aryl hydrocarbon receptor (AHR) is activated by 3-methylcholanthrene (MC), a polycyclic aromatic hydrocarbon, and environmental contaminants, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin. | Methylcholanthrene | aryl hydrocarbon receptor | Rattus norvegicus |
| 5 | The aryl hydrocarbon receptor (AHR) is activated by 3-methylcholanthrene (MC), a polycyclic aromatic hydrocarbon, and environmental contaminants, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin. | Methylcholanthrene | aryl hydrocarbon receptor | Rattus norvegicus |
| 6 | AHR mRNA was induced 4-fold 6 h after MC in SHAM rats, but no induction was observed in ADX rats. | Methylcholanthrene | aryl hydrocarbon receptor | Rattus norvegicus |
| 7 | We have shown that the response to MC in ADX rats is suppressed for some, but not all, AHR-mediated responses and that reduced POR activity after ADX could contribute to a decreased capacity for P450-dependent metabolism. | Methylcholanthrene | aryl hydrocarbon receptor | Rattus norvegicus |