Title : The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by the platinum-based anticancer drugs.

Pub. Date : 2011 Feb

PMID : 20878461






1 Functional Relationships(s)
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Protein Name
Organism
1 The BRCA1 ubiquitin ligase activity was inhibited by transplatin > cisplatin > oxaliplatin > carboplatin in that order. Carboplatin BRCA1 DNA repair associated Homo sapiens