Title : The ecto-enzyme CD38 is a nicotinic acid adenine dinucleotide phosphate (NAADP) synthase that couples receptor activation to Ca2+ mobilization from lysosomes in pancreatic acinar cells.

Pub. Date : 2010 Dec 3

PMID : 20870729






1 Functional Relationships(s)
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1 We propose that CD38 is an NAADP synthase required for coupling receptor activation to NAADP-mediated Ca(2+) release from lysosomal stores in pancreatic acinar cells. NAADP CD38 molecule Rattus norvegicus