Title : Regional absorption of fexofenadine in rat intestine.

Pub. Date : 2010 Dec 23

PMID : 20869437






2 Functional Relationships(s)
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Protein Name
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1 Inhibition of Pgp by PSC-833 affected fexofenadine absorption only in distal segments resulting in AUC values comparable to the proximal data. fexofenadine phosphoglycolate phosphatase Rattus norvegicus
2 CONCLUSION: The study demonstrates that Pgp is responsible for a limitation of fexofenadine absorption from distal small intestine. fexofenadine phosphoglycolate phosphatase Rattus norvegicus