Title : Ecto-5'-nucleotidase and thiopurine cellular circulation: association with cytotoxicity.

Pub. Date : 2010 Dec

PMID : 20855458






1 Functional Relationships(s)
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1 Those observations suggested the possible existence of a "thiopurine cellular circulation" involving nucleotide efflux by ABCC4, hydrolysis of thiopurine nucleotide monophosphates outside of the cell by NT5E, and subsequent transport of thiopurine nucleosides back into the cell by nucleoside transporters. 2-mercaptopyrazine 5'-nucleotidase ecto Homo sapiens