Title : Caffeine modulates tau phosphorylation and affects Akt signaling in postmitotic neurons.

Pub. Date : 2011 Mar

PMID : 20838929






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Caffeine modulates tau phosphorylation and affects Akt signaling in postmitotic neurons. Caffeine AKT serine/threonine kinase 1 Homo sapiens
2 We show that caffeine blocks the cell cycle at G1 phase in neuroblastoma cells and leads to a decrease in tau phosphorylation; similarly, exposure of postmitotic neurons to caffeine led to changes in tau phosphorylation concomitantly with downregulation of Akt signaling. Caffeine AKT serine/threonine kinase 1 Homo sapiens
3 We show that caffeine blocks the cell cycle at G1 phase in neuroblastoma cells and leads to a decrease in tau phosphorylation; similarly, exposure of postmitotic neurons to caffeine led to changes in tau phosphorylation concomitantly with downregulation of Akt signaling. Caffeine AKT serine/threonine kinase 1 Homo sapiens