Title : Phorbol 12-myristate 13-acetate inhibits the antilipolytic action of insulin, probably via the activity of protein kinase Cε.

Pub. Date : 2010 Dec 1

PMID : 20826143






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Inhibitors of phosphatidylinositol 3-kinase (PI3-K), Akt, and phosphodiesterase 3B (PDE3B) diminished the PMA effect. Tetradecanoylphorbol Acetate AKT serine/threonine kinase 1 Homo sapiens
2 PMA inhibited insulin-stimulated phosphorylation of Tyr in insulin receptor beta subunit and Ser/Thr in Akt. Tetradecanoylphorbol Acetate AKT serine/threonine kinase 1 Homo sapiens