Title : Survival benefit with proapoptotic molecular and pathologic responses from dual targeting of mammalian target of rapamycin and epidermal growth factor receptor in a preclinical model of pancreatic neuroendocrine carcinogenesis.

Pub. Date : 2010 Oct 10

PMID : 20823411






1 Functional Relationships(s)
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1 MATERIALS AND METHODS: Rapamycin and erlotinib, inhibitors of mTOR and EGFR, respectively, were used to treat RIP-Tag2 transgenic mice bearing advanced multifocal PNET. Erlotinib Hydrochloride regulation of phenobarbitol-inducible P450 Mus musculus