Title : Modulation of carbonic anhydrase 9 (CA9) in human brain cancer.

Pub. Date : 2010

PMID : 20819065






1 Functional Relationships(s)
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Protein Name
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1 CA IX contributes to tumour environment acidification by catalyzing the carbon dioxide hydration to bicarbonate and protons, leading to the acquisition of metastasic phenotypes and chemoresistance to weakly basic anticancer drugs and therefore to inadequate application of radio-therapeutic or chemotherapeutic anti-cancer treatment strategies. Carbon Dioxide carbonic anhydrase 9 Homo sapiens