Title : Comparison of cytochrome P450 3A enzymes in cynomolgus monkeys and humans.

Pub. Date : 2010

PMID : 20814160






2 Functional Relationships(s)
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Protein Name
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1 Monkey mfCYP3A5 and mfCYP3A4 were highly active in bufuralol 1"-hydroxylation. bufuralol cytochrome P450 family 3 subfamily A member 5 Macaca fascicularis
2 Apparent bufuralol 1"-hydroxylation and dextromethorphan O-demethylation activities of monkey liver microsomes were higher than those of human liver microsomes, possibly because of contributions of mfCYP3A5 to these P450 2D-dependent drug oxidations. bufuralol cytochrome P450 family 3 subfamily A member 5 Macaca fascicularis