Title : PtdIns3P and Rac direct the assembly of the NADPH oxidase on a novel, pre-phagosomal compartment during FcR-mediated phagocytosis in primary mouse neutrophils.

Pub. Date : 2010 Dec 2

PMID : 20813901






1 Functional Relationships(s)
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1 These components form an active complex at the correct time and subcellular location through a series of incompletely understood mutual interactions, regulated, in part, by GTP/GDP exchange on Rac, protein phosphorylation, and binding to lipid messengers. Guanosine Diphosphate thymoma viral proto-oncogene 1 Mus musculus