Title : Protective effect of sulforaphane against cisplatin-induced mitochondrial alterations and impairment in the activity of NAD(P)H: quinone oxidoreductase 1 and γ glutamyl cysteine ligase: studies in mitochondria isolated from rat kidney and in LLC-PK1 cells.

Pub. Date : 2010 Nov 10

PMID : 20732396






1 Functional Relationships(s)
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1 The protective effect of SFN on ROS production and cell viability was prevented by buthionine sulfoximine (BSO), an inhibitor of gammaGCL, and by dicoumarol, an inhibitor of NQO1. Dicumarol NAD(P)H quinone dehydrogenase 1 Sus scrofa