Title : [Effects of STI571 combined with As₂O₃ on proliferation, apoptosis and caspase 3, Bcl-xL expression of K562 cells].

Pub. Date : 2010 Aug

PMID : 20723293






2 Functional Relationships(s)
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1 The STI571 combined with As2O3 can enhance these two effects, increase the expression of caspase-3 mRNA and decrease the expression of bcl-xL mRNA. Arsenic Trioxide caspase 3 Homo sapiens
2 Therefore, the effect of STI571 combined with As2O3 on expression of caspase 3 and bcl-xL mRNA may be one of molecular mechanisms underlying their synergic antileukemia efficacy. Arsenic Trioxide caspase 3 Homo sapiens