Title : Antitumor effect of betulinic acid on human acute leukemia K562 cells in vitro.

Pub. Date : 2010 Aug

PMID : 20714869






3 Functional Relationships(s)
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1 The proportion of cells in G0/G1 and G2/M phases was decreased and that in S phase was increased after K562 cells were treated with BA for 24 h. BA treatment also increased the expression of the pro-apoptotic proteins Bax and caspase-3. betulinic acid BCL2 associated X, apoptosis regulator Homo sapiens
2 The proportion of cells in G0/G1 and G2/M phases was decreased and that in S phase was increased after K562 cells were treated with BA for 24 h. BA treatment also increased the expression of the pro-apoptotic proteins Bax and caspase-3. betulinic acid BCL2 associated X, apoptosis regulator Homo sapiens
3 The antitumor effects of BA were related with up-regulation of the expression of Bax and caspase-3 proteins. betulinic acid BCL2 associated X, apoptosis regulator Homo sapiens