Title : A potent potassium channel blocker from Mesobuthus eupeus scorpion venom.

Pub. Date : 2010 Dec

PMID : 20713119






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 MeuKTX potently blocks rKv1.1, rKv1.2 and hKv1.3 channels with 50% inhibitory concentration (IC(50)) of 203.15 +- 4.06 pM, 8.92 +- 2.3 nM and 171 +- 8.56 pM, respectively, but does not affect rKv1.4, rKv1.5, hKv3.1, rKv4.3, and hERG channels even at 2 muM concentration. meuktx ETS transcription factor ERG Homo sapiens