Title : SAXS and X-ray crystallography suggest an unfolding model for the GDP/GTP conformational switch of the small GTPase Arf6.

Pub. Date : 2010 Oct 1

PMID : 20709080






2 Functional Relationships(s)
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1 SAXS and X-ray crystallography suggest an unfolding model for the GDP/GTP conformational switch of the small GTPase Arf6. Guanosine Diphosphate ADP ribosylation factor 6 Homo sapiens
2 NMR chemical shifts identify this structural disorder in Delta13Arf6-GDP, but not in the closely related Delta17Arf1-GDP, which is consistent with their comparative thermodynamic and hydrodynamic analyses. Guanosine Diphosphate ADP ribosylation factor 6 Homo sapiens